Civil Service Mains Optional MEDICAL SCIENCE

MEDICAL SCIENCE




PAPER - I

1. Human Anatomy:
Applied anatomy including blood and
nerve supply of upper and lower limbs and
joints of shoulder, hip and knee.
Gross anatomy, blood supply and lym-phatic drainage of tongue, thyroid, mam-mary gland, stomach, liver, prostate, go-nads and uterus.
Applied anatomy of diaphragm, perineum
and inguinal region.
Clinical anatomy of kidney, urinary blad-der, uterine tubes, vas deferens.
Embryology:Placenta and placental bar-rier. Development of heart, gut, kidney,
uterus, ovary, testis and their common con-genital abnormalities.
Central and peripheral autonomic ner-vous system : Gross and clinical anatomy
of ventricles of brain, circulation of cere-brospinal fluid; Neural pathways and le-sions of cutaneous sensations, hearing and
vision; Cranial nerves, distribution and
clinical significance; Components of auto-nomic nervous system.

2. Human Physiology:
Conduction and transmission of impulse,
mechanism of contraction, neuromuscular
transmission, reflexes, control of equilib-rium, posture and muscle tone, descend-ing pathways, functions of cerebellum,
basal ganglia, Physiology of sleep and
consciousness.
Endocrine system:Mechanism of action
of hormones, formation, secretion, trans-port, metabolism, function and regulation
of secretion of pancreas and pituitary gland.
Physiology of reproductive system: Men-strual cycle, lactation, pregnancy.
Blood:Development, regulation and fate
of blood cells.
Cardio-vascular,  cardiac output, blood
pressure, regulation of cardiovascular
functions;

3. Biochemistry:
Organ function tests-liver, kidney, thyroid
Protein synthesis.
Vitamins and minerals.
Restriction fragment length polymorphism
(RFLP).
Polymerase chain reaction (PCR).
Radio - immunoassays (RIA).

4.  Pathology:
Inflammation and repair, disturbances of
growth and cancer, Pathogenesis and his-topathology of rheumatic and ischemic
heart disease and diabetes mellitus. Dif-ferentiation between benign, malignant,
primary and metastatic malignancies,
Pathogenesis and histopathology of bron-chogenic carcinoma, carcinoma breast,
oral cancer, cancer cervix, leukemia, Etiol-ogy, pathogenesis and histopathology of -cirrhosis liver, glomerulonephritis, tuber-culosis, acute osteomyelitis.

5. Microbiology:
Humoral and cell mediated immunity
Diseases caused by and laboratory diag-nosis of-l Meningococcus, Salmonella
l Shigella, Herpes, Dengue, Polio
l HIV/AIDS, Malaria, E. Histolytica, Giar-dia
l Candida, Cryptococcus, Aspergillus

6. Pharmacology:
Mechanism of action and side effects of
the following drugs
l Antipyretics and analgesics, Antibiotics,
Antimalaria; Antikala-azar,Antidiabetics
l Antihypertensive, Antidiuretics, General
and cardiac vasodilators, Antiviral, An-tiparasitic, Antifungal, Immunosuppres-sants
l Anticancer

7.  Forensic Medicine and Toxicology:
Forensic examination of injuries and
wounds; Examination of blood and semi-nal stains; poisoning, sedative overdose,
hanging, drowning, burns, DNA and finger
print study.


PAPER - II
1. General Medicine:
Etiology, clinical features, diagnosis and
principles of management (including pre-vention) of: - Tetanus, Rabies, AIDS, Den-gue, Kala-azar, Japanese Encephalitis.
Etiology, clinical features, diagnosis and
principles of management of:
Ischaemic heart disease, pulmonary em-bolism.
Bronchial asthma.
Pleural effusion, tuberculosis, Malabsorp-tion syndromes, acid peptic diseases, Vi-ral hepatitis and cirrhosis of liver.
Glomerulonerphritis and pyelonephritis,
renal failure, nephrotic syndrome, renovas-cular hypertension, complications of dia-betes mellitus, coagulation disorders, leu-kemia, Hypo and hyper thyrodism, menin-gitis and encephalitis.
Imaging in medical problems, ultrasound,
echocardiogram, CT scan, MRI.
Anxiety and Depressive Psychosis and
schizophrenia and ECT.

2. Pediatrics:
Immunization, Baby friendly hospital, con-genital cyanotic heart disease, respiratory
distress syndrome, broncho - pneumonias,
kernicterus. IMNCI classification and man-agement, PEM grading and management.
ARI and Diarrhea of under five and their
management.

3. Dermatology:
Psoriasis, Allergic dermatitis, scabies, ec-

zema, vitiligo, Stevan Johnson’s syndrome,
Lichen Planus.

4. General Surgery:
Clinical features, causes, diagnosis and
principles of management of cleft palate,
harelip.
Laryngeal tumor, oral and esophageal
tumors.
Peripheral arterial diseases, varicose
veins, coarctation of aorta
Tumors of Thyroid, Adrenal Glands
Abscess, cancer, fibroadenoma and
adenosis of breast.
Bleeding peptic ulcer, tuberculosis of
bowel, ulcerative colitis, cancer stomach.
Renal mass,cancer Prostate..
Haemothorax, stones of Gall bladder, Kid-ney, Ureter and Urinary Bladder.
Management of surgical conditions of Rec-tum, Anus and Anal canal, Gall bladder
and Bile ducts
Splenomegaly, cholecystitis, portal hyper-tension, liver abscess, peritonitis, carci-noma head of pancreas.
Fractures of spine, Colles’ fracture and
bone tumors.
Endoscopy
Laprascopic Surgery.

5. Obstetrics and Gynaecology includ-ing Family Planning:
Diagnosis of pregnancy.
Labour management, complications of 3rd
stage, Antepartum and postpartum hem-orrhage, resuscitation of the newborn,
Management of abnormal lie and difficult
labour, Management of small for date or
premature newborn.
Diagnosis and management of anemia.
Preeclampsia and Toxaemias of preg-nancy, Management of Post menopausal
Syndrome.
Intra-uterine devices, pills, tubectomy and
vasectomy. Medical termination of preg-nancy including legal aspects.
Cancer cervix.
Leucorrhoea, pelvic pain, infertility, dys-functional uterine bleeding (DUB), amen-orrhoea, Fibroid and prolapse of uterus.

6. Community Medicine (Preventive and
Social Medicine):
Principles, methods, approach and mea-surements of Epidemiology
Nutrition, nutritional diseases / disorders &
Nutrition Programmes.
Health information Collection, Analysis and
Presentation.
Objectives, components and critical analy-sis of National programmes for control/
eradication of:
Malaria, Kala-azar, Filaria and Tuberculo-sis,
HIV/AIDS, STDs and Dengue
Critical appraisal of Health care delivery
system.
Health management and administration:
Techniques, Tools, Programme Implemen-tation and Evaluation.
Objective, Component, Goals and Status
of Reproductive and Child Health, National
Rural Health Mission and Millennium De-velopment Goals
Management of hospital and industrial
waste